Speakers

Janine Austin Clayton, M.D. FARVO, Associate Director for Research on Women’s Health and Director of the Office of Research on Women’s Health (ORWH) at the National Institutes of Health (NIH), is the architect of the NIH policy requiring scientists to consider sex as a biological variable across the research spectrum. This effort is part of NIH’s initiative to enhance reproducibility through rigor and transparency. Prior to joining the ORWH, Dr. Clayton was the Deputy Clinical Director of the National Eye Institute. A board-certified fellowship-trained ophthalmologist, Dr. Clayton’s research interests include autoimmune ocular diseases and sex influences in health and disease. She served as an elected member of the Board of Directors of the American Association for the Advancement of Science (2021-2025) and was elected to the National Academy of Medicine in 2024. Dr. Clayton has been recognized as a leader by her peers with the American Medical Association’s Nathan Davis Award for Outstanding Government Service (2017), as a Luminary Honoree by the Precision Medicine World Congress (2024) and received the Public Service Visionary Award from the Society for Women’s Health Research (2024). She is the author of more than 150 scientific publications, journal articles, and book chapters.   

A physician first and foremost, Dr. John D’Angelo leads with compassion. With over 25 years of practical experience, he continues to transform health care operations with his recent appointment as president and CEO of Northwell health, the Northeast’s largest non-for-profit health system.

Dr. D’Angelo oversees a complex network of 28 hospitals and 104,000 employees, including over 1,000 outpatient facilities, 22,000 nurses and over 20,000 physicians with an operating budget of $22.6 billion. Northwell cares for more than three million people annually in the New York metro area, including Long Island, the Hudson Valley, western Connecticut and beyond.

His background in emergency medicine informed his leadership in Northwell’s operational response to COVID-19, expanding his role to become the chief of integrated operations for the entire health system. He also co-led an award-winning, innovative data solution, Real-Time Actionable Data, to enhance operational visibility. Previously, he oversaw all of Northwell’s emergency departments and was instrumental in the health system’s lifesaving sepsis prevention initiatives.

A Long Island native, Dr. D’Angelo received his medical degree from SUNY Stony Brook and subsequently completed a residency in emergency medicine at Geisinger Medical Center, Danville, PA. He also served as medical director to numerous EMS agencies throughout his career and served in the United States Army Reserve from 2001-2011.

Dr. Kalman received her bachelor’s degree in history and art history from the University of Pennsylvania and medical degree from the Mount Sinai School of Medicine. She performed all her clinical training (internal medicine residency, chief medical residency, clinical cardiology, advanced heart failure) at Mount Sinai, New York. She has also completed a physician leadership course at the Health Management Academy and a health care delivery executive program at the Harvard University School of Business. Dr. Kalman began her professional career as an academic cardiologist, directing clinical and research heart failure programs at Beth Israel Medical Center, Tisch Hospital at New York University, and Mount Sinai Medical Center. In addition to her outstanding clinical skills and dedication to patients, Dr. Kalman was tremendously effective in organizing and galvanizing clinical, research, and administrative programs focused on the needs of complex patients with advanced heart failure. 
 
She came to Northwell Health in 2014 as associate medical director of Long Island Jewish Medical Center and the North Shore LIJ Health System. She then moved to Lenox Hill Hospital as medical director (2015-2018) and was also the health system’s medical director of patient experience (2016-2021). In 2018, Dr. Kalman became executive director of Lenox Hill Hospital and showed exemplary leadership during the pandemic. 
 
In 2021, she was appointed chief medical officer and deputy physician-in-chief at Northwell Health. Dr. Kalman is truly a visionary leader, a champion of excellence, innovator, and a strategic mind. She is a professor of cardiology at the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell. 
 
She is a well-recognized, highly respected national health care trailblazer and has helped put Northwell on the national map in many areas, including innovation, AI, patient experience, women’s health, physician wellness, crisis management, and effective change. 
 
Dr. Kalman has received Modern Healthcare Top Women Leaders Award, the Long Island Herald Excellence in Healthcare Award, chaired the American Heart Association’s Go Red Campaign, and been recognized by Becker’s as a Chief Medical Officer to Know and by Reuters as one of Healthcare’s Trailblazing Women. 

Holly Maloney is a career-long investor and serves as Managing Director and Head of Health Assurance at General Catalyst, a venture capital and transformation company. At GC, Holly invests across stages and business models, focusing on companies redefining the future of health. Her portfolio includes Judi Health, Maven, Adonis, Equip, Fabric, Sprinter, SonderMind, Teamworks, Transcarent, Zarmeni, InStride, Newdays.AI, Sage Care, Leona, and Almanac. Holly received a BA in Economics from Bowdoin College, where she is now a Trustee and a member of its Investment Committee. She lives in Marin County, CA with her husband, two daughters and golden retriever.

Congresswoman Lauren Underwood serves Illinois’ 14th Congressional District and was first sworn into Congress on January 3, 2019. She is the first woman, the first person of color, and the first millennial to represent her community in Congress.  

Rep. Underwood is a registered nurse and co-founder and co-chair of the Black Maternal Health Caucus, which addresses America’s Black Maternal Health crisis in Congress and advances policy solutions to improve maternal health outcomes and end disparities. Rep. Underwood is Co-Chair of the House Democratic Policy and Communications Committee and serves on the House Committee on Appropriations. 

Prior to her election to Congress, she served as a Senior Advisor at the U.S. Department of Health and Human Services (HHS), helping communities across the country prevent, prepare for, and respond to disasters, bioterror threats, and public health emergencies. As a career public servant at HHS, she also helped implement the Affordable Care Act, broadening access for those on Medicare, improving health care quality, and reforming private insurance. Rep. Underwood has taught future nurse practitioners through Georgetown University’s online master’s program and worked with a Medicaid plan in Chicago to ensure it provided high-quality, cost-efficient care.  

She is a graduate of the University of Michigan and Johns Hopkins University, and a lifelong Girl Scout. Rep. Underwood resides in Naperville, Illinois.